| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM279577 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | [3H]PK 11195 radio-assay |
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| Ki | 60.0±n/a nM |
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| Citation |  Gavish, M; Veenman, JA; Shterenberg, A; Marek, I; Vainshtein, A; Avital, A Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof US Patent US10035780 Publication Date 7/31/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 18834.74 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30536 |
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| Residue: | 169 |
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| Sequence: | MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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| BDBM279577 |
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| n/a |
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| Name | BDBM279577 |
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| Synonyms: | US10035780, Compound 1 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N3O2 |
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| Mol. Mass. | 307.3465 |
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| SMILES | CCN(C)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1 |
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| Structure | 
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