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TargetTranslocator protein
LigandBDBM279581
Substrate/Competitorn/a
Meas. Tech.[3H]PK 11195 radio-assay
Ki 600±n/a nM
Citation Gavish, MVeenman, JAShterenberg, AMarek, IVainshtein, AAvital, A Quinazoline scaffold based compounds, pharmaceutical compositions and methods of use thereof US Patent US10035780 Publication Date 7/31/2018
More Info.:Get all data from this article,  Assay Method
 
Translocator protein
Name:Translocator protein
Synonyms:BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:Enzyme
Mol. Mass.:18834.74
Organism:Homo sapiens (Human)
Description:P30536
Residue:169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAM
GYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAA
ATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
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  Blast E-value cutoff:
BDBM279581
n/a
NameBDBM279581
Synonyms:US10035780, Compound 5
TypeSmall organic molecule
Emp. Form.C17H14ClN3O2
Mol. Mass.327.765
SMILESCN(C)C(=O)Oc1nc(nc2ccccc12)-c1ccccc1Cl
Structure
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