Reaction Details |
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Target | Prostaglandin G/H synthase 1 [582-599] |
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Ligand | BDBM93104 |
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Substrate/Competitor | n/a |
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Meas. Tech. | In Vitro COX Inhibition Assay |
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IC50 | >1.00e+5±n/a nM |
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Citation | Zarghi, A; Arefi, H; Dadrass, OG; Torabi, S Design and synthesis of new 2-aryl, 3-benzyl- (1,3-oxazolidine or 1,3-thiazolidine)-4-ones as selective cyclooxygenase (COX-2) inhibitor Med Chem Res19:782-793 (2009) |
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More Info.: | Get all data from this article, Assay Method |
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Prostaglandin G/H synthase 1 [582-599] |
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Name: | Prostaglandin G/H synthase 1 [582-599] |
Synonyms: | COX-1 | COX1 | Cyclooxygenase | Cyclooxygenase-1 | Cyclooxygenase-1 (COX-1) | PGH synthase 1 | PGH1_HUMAN | PGHS-1 | PHS 1 | PTGS1 | Prostaglandin G/H synthase 1 | Prostaglandin H2 synthase 1 | Prostaglandin-endoperoxide synthase 1 |
Type: | Protein |
Mol. Mass.: | 1879.89 |
Organism: | Homo sapiens (Human) |
Description: | Q6LCE7 |
Residue: | 18 |
Sequence: | |
BDBM93104 |
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n/a |
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Name | BDBM93104 |
Synonyms: | COX inhibitor, 5b |
Type | Small molecule |
Emp. Form. | C16H15NOS |
Mol. Mass. | 269.361 |
SMILES | O=C1CSC(N1Cc1ccccc1)c1ccccc1 |
Structure |
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