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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Dual specificity protein kinase CLK2 | ||
| Ligand | BDBM93225 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 2.5e+4±n/a nM | ||
| Citation |  Urich, R; Wishart, G; Kiczun, M; Richters, A; Tidten-Luksch, N; Rauh, D; Sherborne, B; Wyatt, PG; Brenk, R De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments. ACS Chem Biol8:1044-52 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Dual specificity protein kinase CLK2 | |||
| Name: | Dual specificity protein kinase CLK2 | ||
| Synonyms: | 2.7.12.1 | CDC-like kinase 2 | CDC-like kinase 2 (CLK2) | CDC2-like kinase 2 (CLK2) | CLK2 | CLK2_HUMAN | ||
| Type: | n/a | ||
| Mol. Mass.: | 60128.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P49760 | ||
| Residue: | 499 | ||
| Sequence: |
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| BDBM93225 | |||
| n/a | |||
| Name | BDBM93225 | ||
| Synonyms: | Kinase inhibitor, A2 | ||
| Type | Small molecule | ||
| Emp. Form. | C14H9F2N3O | ||
| Mol. Mass. | 273.2376 | ||
| SMILES | Nc1cnc2c(cccn2c1=O)-c1c(F)cccc1F |(-3.92,1.6,;-5.25,2.37,;-5.25,3.91,;-6.59,4.68,;-7.92,3.91,;-9.25,4.68,;-10.59,3.91,;-10.59,2.37,;-9.25,1.6,;-7.92,2.37,;-6.59,1.6,;-6.59,.06,;-9.25,6.22,;-10.59,6.99,;-11.92,6.22,;-10.59,8.53,;-9.25,9.3,;-7.92,8.53,;-7.92,6.99,;-6.59,6.22,)| | ||
| Structure | 
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