| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
|---|
| Ligand | BDBM81214 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 1000±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Corticotropin-releasing factor-binding protein |
|---|
| Name: | Corticotropin-releasing factor-binding protein |
|---|
| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 36143.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P24387 |
|---|
| Residue: | 322 |
|---|
| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
|
|
|
|---|
| BDBM81214 |
|---|
| n/a |
|---|
| Name | BDBM81214 |
|---|
| Synonyms: | 3-methyl-5-(4-nitrophenyl)azo-2-sulfanylidene-4-thiazolidinone | 3-methyl-5-(4-nitrophenyl)azo-2-thioxo-thiazolidin-4-one | 3-methyl-5-[(4-nitrophenyl)diazenyl]-2-sulfanylidene-1,3-thiazolidin-4-one | MLS002608645 | SMR001527391 | cid_13752 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H8N4O3S2 |
|---|
| Mol. Mass. | 296.326 |
|---|
| SMILES | Cn1c(O)c(N=Nc2ccc(cc2)[N+]([O-])=O)sc1=S |w:5.4| |
|---|
| Structure | 
|
|---|
Search and Browse
