| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM89721 |
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| Substrate/Competitor | n/a |
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| IC50 | 941±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM89721 |
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| n/a |
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| Name | BDBM89721 |
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| Synonyms: | 5-[(2-chloranyl-4-fluoranyl-phenyl)methylsulfanyl]-1,3,4-thiadiazol-2-amine | 5-[(2-chloro-4-fluorobenzyl)thio]-1,3,4-thiadiazol-2-amine | 5-[(2-chloro-4-fluorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-amine | 5-[(2-chloro-4-fluorophenyl)methylthio]-1,3,4-thiadiazol-2-amine | MLS000064707 | SMR000077501 | [5-[(2-chloro-4-fluoro-benzyl)thio]-1,3,4-thiadiazol-2-yl]amine | cid_972610 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H7ClFN3S2 |
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| Mol. Mass. | 275.753 |
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| SMILES | Nc1nnc(SCc2ccc(F)cc2Cl)s1 |
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| Structure | 
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