| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
|---|
| Ligand | BDBM63534 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 675±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Corticotropin-releasing factor-binding protein |
|---|
| Name: | Corticotropin-releasing factor-binding protein |
|---|
| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 36143.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P24387 |
|---|
| Residue: | 322 |
|---|
| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
|
|
|
|---|
| BDBM63534 |
|---|
| n/a |
|---|
| Name | BDBM63534 |
|---|
| Synonyms: | 8-methoxy-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-1-benzopyran-2-one | 8-methoxy-3-(5-phenyl-1,3,4-oxadiazol-2-yl)chromen-2-one | 8-methoxy-3-(5-phenyl-1,3,4-oxadiazol-2-yl)coumarin | MLS000687822 | SMR000284886 | cid_748239 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H12N2O4 |
|---|
| Mol. Mass. | 320.2989 |
|---|
| SMILES | COc1cccc2cc(-c3nnc(o3)-c3ccccc3)c(=O)oc12 |
|---|
| Structure | 
|
|---|
Search and Browse
