Reaction Details |
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Target | Corticotropin-releasing factor-binding protein |
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Ligand | BDBM91415 |
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Substrate/Competitor | n/a |
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IC50 | 5280±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article |
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Corticotropin-releasing factor-binding protein |
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Name: | Corticotropin-releasing factor-binding protein |
Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 36143.95 |
Organism: | Homo sapiens (Human) |
Description: | P24387 |
Residue: | 322 |
Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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BDBM91415 |
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n/a |
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Name | BDBM91415 |
Synonyms: | 2-[6-(diethylamino)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g][1]benzopyran-8-yl]-6-methoxyphenol | 2-[6-(diethylamino)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-8-yl]-6-methoxy-phenol | 2-[6-(diethylamino)-7-methyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-8-yl]-6-methoxyphenol | MLS002702192 | SMR001565755 | cid_381395 |
Type | Small organic molecule |
Emp. Form. | C22H27NO5 |
Mol. Mass. | 385.4535 |
SMILES | CCN(CC)C1Oc2cc3OCOc3cc2C(C1C)c1cccc(OC)c1O |
Structure |
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