| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM90092 |
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| Substrate/Competitor | n/a |
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| IC50 | 4640±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM90092 |
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| n/a |
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| Name | BDBM90092 |
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| Synonyms: | MLS000332372 | N-[4-(4-Methoxy-phenyl)-thiazol-2-yl]-2-(3-methylsulfanyl-[1,2,4]thiadiazol-5-ylsulfanyl)-acetamide | N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]acetamide | N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-2-[(3-methylsulfanyl-1,2,4-thiadiazol-5-yl)sulfanyl]ethanamide | N-[4-(4-methoxyphenyl)-2-thiazolyl]-2-[[3-(methylthio)-1,2,4-thiadiazol-5-yl]thio]acetamide | N-[4-(4-methoxyphenyl)thiazol-2-yl]-2-[[3-(methylthio)-1,2,4-thiadiazol-5-yl]thio]acetamide | SMR000221674 | cid_1840505 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O2S4 |
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| Mol. Mass. | 410.557 |
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| SMILES | COc1ccc(cc1)-c1csc(NC(=O)CSc2nc(SC)ns2)n1 |
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| Structure | 
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