Reaction Details | |||
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Target | Methionine--tRNA ligase | ||
Ligand | BDBM95857 | ||
Substrate/Competitor | n/a | ||
IC50 | 672.14±n/a nM | ||
Citation | PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS) PubChem Bioassay(2013)[AID] | ||
More Info.: | Get all data from this article | ||
Methionine--tRNA ligase | |||
Name: | Methionine--tRNA ligase | ||
Synonyms: | methionyl-tRNA synthetase | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 86905.45 | ||
Organism: | Trypanosoma brucei brucei strain 927/4 GUTat10.1 | ||
Description: | gi_71746704 | ||
Residue: | 773 | ||
Sequence: |
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BDBM95857 | |||
n/a | |||
Name | BDBM95857 | ||
Synonyms: | (2S,3R,12bS)-2-((benzo[d][1,3]dioxol-5-ylmethyl)(methyl)amino)-3-((S)-1-hydroxyethyl)-1,2,3,6,7,12b-hexahydroindolo[2,3-a]quinolizin-4(12H)-one | (2S,3R,12bS)-2-[1,3-benzodioxol-5-ylmethyl(methyl)amino]-3-[(1S)-1-hydroxyethyl]-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one | (2S,3R,12bS)-2-[1,3-benzodioxol-5-ylmethyl(methyl)amino]-3-[(1S)-1-oxidanylethyl]-2,3,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-4-one | (2S,3R,12bS)-3-[(1S)-1-hydroxyethyl]-2-[methyl(piperonyl)amino]-2,3,6,7,12,12b-hexahydro-1H-pyrido[2,1-a]-carbolin-4-one | MLS002920945 | SMR001798410 | cid_46902355 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H29N3O4 | ||
Mol. Mass. | 447.5262 | ||
SMILES | C[C@H](O)[C@H]1[C@H](C[C@@H]2N(CCc3c2[nH]c2ccccc32)C1=O)N(C)Cc1ccc2OCOc2c1 | ||
Structure |