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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Macrophage colony-stimulating factor 1 | ||
| Ligand | BDBM97735 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Fluorescence Polarization Competition Immunoassay | ||
| pH | 7.5±0 | ||
| IC50 | 3±n/a nM | ||
| Citation |  Illig, CR; Ballentine, SK; Chen, J; DesJarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent US8481564 Publication Date 7/9/2013 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Macrophage colony-stimulating factor 1 | |||
| Name: | Macrophage colony-stimulating factor 1 | ||
| Synonyms: | CSF1_MOUSE | Csf1 | Csfm | Macrophage colony-stimulating factor 1 (CSF-1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 60631.84 | ||
| Organism: | Mus musculus (Mouse) | ||
| Description: | P07141 | ||
| Residue: | 552 | ||
| Sequence: |
| ||
| BDBM97735 | |||
| n/a | |||
| Name | BDBM97735 | ||
| Synonyms: | US8481564, 12 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H22N8O | ||
| Mol. Mass. | 414.4631 | ||
| SMILES | O=C(Nc1ccc(cc1C1=CCCCC1)C1CNC(NC1)=NC#N)c1nc(c[nH]1)C#N |t:10,(6.88,1.32,;5.55,.55,;4.22,1.32,;2.88,.55,;2.88,-.99,;1.55,-1.76,;.22,-.99,;.22,.55,;1.55,1.32,;1.55,2.86,;2.88,3.63,;2.88,5.17,;1.55,5.94,;.22,5.17,;.22,3.63,;-1.12,-1.76,;-1.12,-3.3,;-2.45,-4.07,;-3.78,-3.3,;-3.78,-1.76,;-2.45,-.99,;-5.12,-4.07,;-6.45,-3.3,;-7.79,-2.53,;6.32,-.78,;5.42,-2.03,;6.32,-3.27,;7.79,-2.8,;7.79,-1.26,;5.55,-4.61,;4.78,-5.94,)| | ||
| Structure | 
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