Reaction Details | |||
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Target | Macrophage colony-stimulating factor 1 | ||
Ligand | BDBM97739 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Fluorescence Polarization Competition Immunoassay | ||
pH | 7.5±0 | ||
IC50 | 0.42±n/a nM | ||
Citation | Illig, CR; Ballentine, SK; Chen, J; DesJarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent US8481564 Publication Date 7/9/2013 | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Macrophage colony-stimulating factor 1 | |||
Name: | Macrophage colony-stimulating factor 1 | ||
Synonyms: | CSF1_MOUSE | Csf1 | Csfm | Macrophage colony-stimulating factor 1 (CSF-1) | ||
Type: | Protein | ||
Mol. Mass.: | 60631.84 | ||
Organism: | Mus musculus (Mouse) | ||
Description: | P07141 | ||
Residue: | 552 | ||
Sequence: |
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BDBM97739 | |||
n/a | |||
Name | BDBM97739 | ||
Synonyms: | US8481564, 54 | ||
Type | Small organic molecule | ||
Emp. Form. | C26H30N8O | ||
Mol. Mass. | 470.5694 | ||
SMILES | CN1CC(CN(C)C1=NC#N)c1ccc(NC(=O)c2nc(c[nH]2)C#N)c(c1)C1=CCC(C)(C)CC1 |t:30,(-8.73,-1.92,;-7.39,-2.69,;-6.06,-1.93,;-4.73,-2.69,;-4.73,-4.23,;-6.06,-5,;-6.06,-6.54,;-7.39,-4.23,;-8.73,-5,;-8.73,-6.54,;-8.73,-8.08,;-3.39,-1.93,;-2.06,-2.69,;-.72,-1.93,;-.72,-.38,;.61,.38,;1.94,-.38,;1.94,-1.93,;3.28,.38,;3.28,1.93,;4.74,2.4,;5.65,1.15,;4.74,-.09,;5.51,3.73,;6.28,5.07,;-2.06,.38,;-3.39,-.38,;-2.06,1.93,;-.72,2.69,;-.72,4.23,;-2.06,5,;-3.15,6.09,;-.72,5.77,;-3.39,4.23,;-3.39,2.69,)| | ||
Structure |