| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein [1027-1657] |
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| Ligand | BDBM97758 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 2±n/a nM |
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| Comments | extracted |
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| Citation |  Casarez, A; Ji, M; Kim, CU; Sheng, XC; Wu, Q Antiviral compounds US Patent US8476225 Publication Date 7/2/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein [1027-1657] |
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| Name: | Genome polyprotein [1027-1657] |
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| Synonyms: | POLG_HCV1 | Serine protease NS3 |
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| Type: | n/a |
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| Mol. Mass.: | 67260.74 |
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| Organism: | Hepatitis C virus genotype 1a (isolate 1) (HCV) |
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| Description: | 1027-1657 aa of P26664 |
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| Residue: | 631 |
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| Sequence: | APITAYAQQTRGLLGCIITSLTGRDKNQVEGEVQIVSTAAQTFLATCINGVCWTVYHGAG
TRTIASPKGPVIQMYTNVDQDLVGWPAPQGSRSLTPCTCGSSDLYLVTRHADVIPVRRRG
DSRGSLLSPRPISYLKGSSGGPLLCPAGHAVGIFRAAVCTRGVAKAVDFIPVENLETTMR
SPVFTDNSSPPVVPQSFQVAHLHAPTGSGKSTKVPAAYAAQGYKVLVLNPSVAATLGFGA
YMSKAHGIDPNIRTGVRTITTGSPITYSTYGKFLADGGCSGGAYDIIICDECHSTDATSI
LGIGTVLDQAETAGARLVVLATATPPGSVTVPHPNIEEVALSTTGEIPFYGKAIPLEVIK
GGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLDVSVIPTSGDVVVVATDALMTGYTG
DFDSVIDCNTCVTQTVDFSLDPTFTIETITLPQDAVSRTQRRGRTGRGKPGIYRFVAPGE
RPSGMFDSSVLCECYDAGCAWYELTPAETTVRLRAYMNTPGLPVCQDHLEFWEGVFTGLT
HIDAHFLSQTKQSGENLPYLVAYQATVCARAQAPPPSWDQMWKCLIRLKPTLHGPTPLLY
RLGAVQNEITLTHPVTKYIMTCMSADLEVVT
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| BDBM97758 |
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| n/a |
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| Name | BDBM97758 |
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| Synonyms: | US8476225, 19 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H42ClN5O9S2 |
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| Mol. Mass. | 728.276 |
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| SMILES | CC(C)(C)[C@H](NC(=O)OC1CCCC1)C(=O)N1CN(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)C1CC1)S(=O)(=O)c1ccc(Cl)cc1 |r| |
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| Structure | 
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