Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Reverse transcriptase protein | ||
| Ligand | BDBM2158 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| IC50 | 90000±n/a nM | ||
| Citation |  Bode, ML; Rousseau, AL; Gravestock, D; Moleele, SS; Van Der Westhuyzen, CW Imidazopyridines and imidazopyrimidines as HIV-1 reverse transcriptase inhibitors US Patent US8501767 Publication Date 8/6/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Reverse transcriptase protein | |||
| Name: | Reverse transcriptase protein | ||
| Synonyms: | n/a | ||
| Type: | Protein | ||
| Mol. Mass.: | 30157.99 | ||
| Organism: | Human immunodeficiency virus 1 | ||
| Description: | Q9WJP9 | ||
| Residue: | 259 | ||
| Sequence: |
| ||
| BDBM2158 | |||
| n/a | |||
| Name | BDBM2158 | ||
| Synonyms: | DG 402-49648 | US8501787, 74 | ||
| Type | n/a | ||
| Emp. Form. | C20H21ClFN3 | ||
| Mol. Mass. | 357.852 | ||
| SMILES | Cc1ccc(Cl)c(-c2nc3ccccn3c2NC2CCCCC2)c1F |(6.16,-.4,;5.39,.93,;6.16,2.27,;5.39,3.6,;3.85,3.6,;3.08,4.93,;3.08,2.27,;1.54,2.27,;.64,3.51,;-.83,3.04,;-2.16,3.81,;-3.49,3.04,;-3.49,1.5,;-2.16,.73,;-.83,1.5,;.64,1.02,;1.04,-.47,;.22,-1.59,;-1.27,-1.2,;-2.36,-2.29,;-1.96,-3.77,;-.47,-4.17,;.62,-3.08,;3.85,.93,;3.08,-.4,)| | ||
| Structure | 
| ||