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TargetKallikrein-7
LigandBDBM100081
Substrate/Competitorn/a
EC50>285.84±n/a nM
Citation PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID]
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Kallikrein-7
Name:Kallikrein-7
Synonyms:KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:PROTEIN
Mol. Mass.:27535.05
Organism:Homo sapiens (Human)
Description:ChEMBL_1469257
Residue:253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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BDBM100081
n/a
NameBDBM100081
Synonyms:4-[[2-(4-fluorophenyl)-4-keto-1,2-dihydroquinazolin-3-yl]amino]-4-keto-butyric acid | 4-[[2-(4-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]amino]-4-oxidanylidene-butanoic acid | 4-[[2-(4-fluorophenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]amino]-4-oxobutanoic acid | MLS000779206 | N-[2-(4-Fluoro-phenyl)-4-oxo-1,4-dihydro-2H-quinazolin-3-yl]-succinamic acid | SMR000415899 | cid_4888929
TypeSmall organic molecule
Emp. Form.C18H16FN3O4
Mol. Mass.357.3357
SMILESOC(=O)CCC(=O)NN1C(Nc2ccccc2C1=O)c1ccc(F)cc1
Structure
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