Reaction Details |
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Target | Kallikrein-7 |
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Ligand | BDBM100081 |
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Substrate/Competitor | n/a |
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EC50 | >285.84±n/a nM |
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Citation | PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article |
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Kallikrein-7 |
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Name: | Kallikrein-7 |
Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
Type: | PROTEIN |
Mol. Mass.: | 27535.05 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1469257 |
Residue: | 253 |
Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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BDBM100081 |
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n/a |
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Name | BDBM100081 |
Synonyms: | 4-[[2-(4-fluorophenyl)-4-keto-1,2-dihydroquinazolin-3-yl]amino]-4-keto-butyric acid | 4-[[2-(4-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]amino]-4-oxidanylidene-butanoic acid | 4-[[2-(4-fluorophenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]amino]-4-oxobutanoic acid | MLS000779206 | N-[2-(4-Fluoro-phenyl)-4-oxo-1,4-dihydro-2H-quinazolin-3-yl]-succinamic acid | SMR000415899 | cid_4888929 |
Type | Small organic molecule |
Emp. Form. | C18H16FN3O4 |
Mol. Mass. | 357.3357 |
SMILES | OC(=O)CCC(=O)NN1C(Nc2ccccc2C1=O)c1ccc(F)cc1 |
Structure |
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