Reaction Details |
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Target | Kallikrein-7 |
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Ligand | BDBM75191 |
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Substrate/Competitor | n/a |
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EC50 | >858.21±n/a nM |
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Citation | PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article |
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Kallikrein-7 |
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Name: | Kallikrein-7 |
Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
Type: | PROTEIN |
Mol. Mass.: | 27535.05 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1469257 |
Residue: | 253 |
Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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BDBM75191 |
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n/a |
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Name | BDBM75191 |
Synonyms: | 2-[7-hydroxy-2-keto-4-methyl-8-[(veratrylamino)methyl]chromen-3-yl]acetic acid methyl ester;hydrochloride | 2-[8-[[(3,4-dimethoxyphenyl)methylamino]methyl]-7-hydroxy-4-methyl-2-oxo-1-benzopyran-3-yl]acetic acid methyl ester;hydrochloride | MLS001216010 | SMR000544745 | cid_24761148 | methyl 2-[8-[[(3,4-dimethoxyphenyl)methylamino]methyl]-4-methyl-7-oxidanyl-2-oxidanylidene-chromen-3-yl]ethanoate;hydrochloride | methyl 2-[8-[[(3,4-dimethoxyphenyl)methylamino]methyl]-7-hydroxy-4-methyl-2-oxochromen-3-yl]acetate;hydrochloride |
Type | Small organic molecule |
Emp. Form. | C23H25NO7 |
Mol. Mass. | 427.4471 |
SMILES | COC(=O)Cc1c(C)c2ccc(O)c(CNCc3ccc(OC)c(OC)c3)c2oc1=O |
Structure |
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