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TargetKallikrein-7
LigandBDBM75191
Substrate/Competitorn/a
EC50>858.21±n/a nM
Citation PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID]
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Kallikrein-7
Name:Kallikrein-7
Synonyms:KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:PROTEIN
Mol. Mass.:27535.05
Organism:Homo sapiens (Human)
Description:ChEMBL_1469257
Residue:253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
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BDBM75191
n/a
NameBDBM75191
Synonyms:2-[7-hydroxy-2-keto-4-methyl-8-[(veratrylamino)methyl]chromen-3-yl]acetic acid methyl ester;hydrochloride | 2-[8-[[(3,4-dimethoxyphenyl)methylamino]methyl]-7-hydroxy-4-methyl-2-oxo-1-benzopyran-3-yl]acetic acid methyl ester;hydrochloride | MLS001216010 | SMR000544745 | cid_24761148 | methyl 2-[8-[[(3,4-dimethoxyphenyl)methylamino]methyl]-4-methyl-7-oxidanyl-2-oxidanylidene-chromen-3-yl]ethanoate;hydrochloride | methyl 2-[8-[[(3,4-dimethoxyphenyl)methylamino]methyl]-7-hydroxy-4-methyl-2-oxochromen-3-yl]acetate;hydrochloride
TypeSmall organic molecule
Emp. Form.C23H25NO7
Mol. Mass.427.4471
SMILESCOC(=O)Cc1c(C)c2ccc(O)c(CNCc3ccc(OC)c(OC)c3)c2oc1=O
Structure
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