| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kallikrein-7 |
|---|
| Ligand | BDBM100182 |
|---|
| Substrate/Competitor | n/a |
|---|
| EC50 | >7722±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Kallikrein-7 |
|---|
| Name: | Kallikrein-7 |
|---|
| Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 27535.05 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469257 |
|---|
| Residue: | 253 |
|---|
| Sequence: | MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLV
NERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNS
QARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVY
KDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCK
FTKWINDTMKKHR
|
|
|
|---|
| BDBM100182 |
|---|
| n/a |
|---|
| Name | BDBM100182 |
|---|
| Synonyms: | 1-[2-methyl-1-(2-methylprop-2-enyl)-3-oxidanylidene-indazol-5-yl]-3-(2-thiophen-2-ylethyl)urea | 1-[2-methyl-1-(2-methylprop-2-enyl)-3-oxo-5-indazolyl]-3-(2-thiophen-2-ylethyl)urea | 1-[2-methyl-1-(2-methylprop-2-enyl)-3-oxoindazol-5-yl]-3-(2-thiophen-2-ylethyl)urea | 1-[3-keto-2-methyl-1-(2-methylallyl)indazolin-5-yl]-3-[2-(2-thienyl)ethyl]urea | MLS003119328 | SMR001275245 | cid_49792300 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22N4O2S |
|---|
| Mol. Mass. | 370.469 |
|---|
| SMILES | CC(=C)Cn1n(C)c(=O)c2cc(NC(=O)NCCc3cccs3)ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
