| Reaction Details |
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 | Report a problem with these data |
| Target | COUP transcription factor 2 |
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| Ligand | BDBM100250 |
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| Substrate/Competitor | n/a |
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| IC50 | 3820±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| COUP transcription factor 2 |
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| Name: | COUP transcription factor 2 |
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| Synonyms: | ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45583.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_14149746 |
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| Residue: | 414 |
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| Sequence: | MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQ
GGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRN
CPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSG
YISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITD
QVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVE
KLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRF
GKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
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| BDBM100250 |
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| n/a |
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| Name | BDBM100250 |
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| Synonyms: | MLS001159328 | N-[4-(3,4-dimethoxyphenyl)-1,3-thiazol-2-yl]-1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide | N-[4-(3,4-dimethoxyphenyl)-2-thiazolyl]-1-(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)-4-piperidinecarboxamide | N-[4-(3,4-dimethoxyphenyl)thiazol-2-yl]-1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)isonipecotamide | SMR000708794 | cid_24981266 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27N5O3S2 |
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| Mol. Mass. | 509.644 |
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| SMILES | COc1ccc(cc1OC)-c1csc(NC(=O)C2CCN(CC2)c2ncnc3sc(C)c(C)c23)n1 |
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| Structure | 
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