| Reaction Details |
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 | Report a problem with these data |
| Target | Pro-glucagon |
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| Ligand | BDBM100856 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Glucagon SPA Assay |
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| pH | 7.4±0 |
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| Ki | 87.2±0.0 nM |
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| Citation |  Aspnes, GE; Didiuk, MT; Filipski, KJ; Guzman-Perez, A; Lee, EC; Pfefferkorn, JA; Stevens, BD; Tu, MM Glucagon receptor modulators US Patent US8507533 Publication Date 8/13/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Pro-glucagon |
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| Name: | Pro-glucagon |
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| Synonyms: | GCG | GLUC_HUMAN | Glucagon | Glucagon receptor (GCGR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 20907.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P01275 |
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| Residue: | 180 |
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| Sequence: | MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTS
DYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFI
AWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
|
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|
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| BDBM100856 |
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| n/a |
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| Name | BDBM100856 |
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| Synonyms: | US8507533, 181 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H26F3N5O3 |
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| Mol. Mass. | 489.4901 |
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| SMILES | CC(C)(C)C(Nc1ccc(nc1)-n1cnc(c1)C(F)(F)F)c1ccc(cc1)C(=O)NCCC(O)=O |
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| Structure | 
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