Reaction Details |
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Target | Pro-glucagon |
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Ligand | BDBM100864 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Glucagon SPA Assay |
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pH | 7.4±0 |
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Ki | 44.7±0.0 nM |
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Citation | Aspnes, GE; Didiuk, MT; Filipski, KJ; Guzman-Perez, A; Lee, EC; Pfefferkorn, JA; Stevens, BD; Tu, MM Glucagon receptor modulators US Patent US8507533 Publication Date 8/13/2013 |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Pro-glucagon |
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Name: | Pro-glucagon |
Synonyms: | GCG | GLUC_HUMAN | Glucagon | Glucagon receptor (GCGR) |
Type: | Enzyme |
Mol. Mass.: | 20907.95 |
Organism: | Homo sapiens (Human) |
Description: | P01275 |
Residue: | 180 |
Sequence: | MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTS
DYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFI
AWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
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BDBM100864 |
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n/a |
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Name | BDBM100864 |
Synonyms: | US8507533, 193 |
Type | Small organic molecule |
Emp. Form. | C24H25F3N6O3 |
Mol. Mass. | 502.4889 |
SMILES | OC(=O)CCNC(=O)c1ccc(cc1)C(Nc1cnc(nc1)-n1cnc(c1)C(F)(F)F)C1CCCC1 |
Structure |
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