| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calcitonin gene-related peptide type 1 receptor |
|---|
| Ligand | BDBM100868 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assay |
|---|
| Ki | 0.77±0.0 nM |
|---|
| Citation |  Wood, MR; Bell, IM; Kim, JJ; Selnick, HG; Stump, CA 3- and 6-quinolines with N-attached heterocyclic CGRP receptor antagonists US Patent US8507477 Publication Date 8/13/2013 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calcitonin gene-related peptide type 1 receptor |
|---|
| Name: | Calcitonin gene-related peptide type 1 receptor |
|---|
| Synonyms: | Adrenomedullin receptor AM1; CALCRL/RAMP2 | CALCRL | CALRL_HUMAN | CGRP type 1 receptor | CGRP type 1 receptor mRNA | CGRPR | Calcitonin gene-related peptide (CGRP) receptor | Calcitonin gene-related peptide 1 (CGRP) | Calcitonin receptor-like receptor | Calcitonin receptor-like receptor (CLR) | Human CL receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 52980.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q16602 |
|---|
| Residue: | 461 |
|---|
| Sequence: | MEKKCTLYFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
|
|
|
|---|
| BDBM100868 |
|---|
| n/a |
|---|
| Name | BDBM100868 |
|---|
| Synonyms: | US8507477, 9 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H30F2N4O2 |
|---|
| Mol. Mass. | 564.6244 |
|---|
| SMILES | Fc1cc(F)cc(c1)[C@@H]1CCC2(CCCC2)C(=O)N1Cc1cnc2cc3C[C@]4(Cc3cc2c1)C(=O)Nc1ncccc41 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
