| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase PAK 4 |
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| Ligand | BDBM101518 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Assay |
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| Ki | 25±n/a nM |
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| EC50 | 32±0 nM |
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| Citation |  Zhang, J; Guo, C; Bouzida, D; Dong, L; Li, H; Marakovits, JT; Yang, A; Hong, Y Pyrrolopyrazoles, potent kinase inhibitors US Patent US8530652 Publication Date 9/10/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase PAK 4 |
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| Name: | Serine/threonine-protein kinase PAK 4 |
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| Synonyms: | KIAA1142 | PAK4 | PAK4_HUMAN | p21-Activated kinase 4 (PAK4) |
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| Type: | Protein |
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| Mol. Mass.: | 64098.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O96013 |
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| Residue: | 591 |
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| Sequence: | MFGKRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLVDPACIT
SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRDSPPPPARARQENGMPEE
PATTARGGPGKAGSRGRFAGHSEAGGGSGDRRRAGPEKRPKSSREGSGGPQESSRDKRPL
SGPDVGTPQPAGLASGAKLAAGRPFNTYPRADTDHPSRGAQGEPHDVAPNGPSAGGLAIP
QSSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTPAAPAVPGPPGPRSPQREPQRVS
HEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRR
ELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAV
CLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPY
WMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHK
VSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR
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| BDBM101518 |
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| n/a |
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| Name | BDBM101518 |
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| Synonyms: | US8524699, 46 | US8530652, 45 | US8530652, 90 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22F3N7OS |
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| Mol. Mass. | 513.538 |
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| SMILES | CC1(C)N(Cc2c(Nc3nc(nc4ccsc34)C(F)(F)F)[nH]nc12)C(=O)N[C@@H]1C[C@H]1c1ccccc1 |r| |
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| Structure | 
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