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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101663 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 26±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM101663 | |||
| n/a | |||
| Name | BDBM101663 | ||
| Synonyms: | US8530504, 24 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H31N3O4S | ||
| Mol. Mass. | 433.564 | ||
| SMILES | CCCN(CCC)c1c(OC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC |(1.46,6.15,;.37,5.06,;-1.12,5.46,;-2.21,4.37,;-3.7,4.77,;-4.09,6.25,;-5.58,6.65,;-1.81,2.88,;-2.72,1.63,;-4.26,1.63,;-5.03,.3,;-1.81,.39,;-.35,.86,;1.12,.39,;2.02,1.63,;1.12,2.88,;-.35,2.4,;1.52,-1.1,;3.01,-1.5,;4.09,-.41,;5.58,-.81,;3.4,-2.99,;2.32,-4.08,;2.71,-5.56,;1.62,-6.65,;.14,-6.25,;.83,-3.68,;.43,-2.19,;-1.06,-1.79,;-2.15,-2.88,)| | ||
| Structure | 
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