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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101666 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 40±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM101666 | |||
| n/a | |||
| Name | BDBM101666 | ||
| Synonyms: | US8530504, 28 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H33N3O5S | ||
| Mol. Mass. | 463.59 | ||
| SMILES | CCCCN(CCOC)c1c(OC)nn2c(csc12)-c1c(OC)cc(COC)cc1OC |(3.14,4.66,;1.66,5.06,;.57,3.97,;-.92,4.37,;-2.01,3.28,;-3.5,3.68,;-3.9,5.16,;-5.38,5.56,;-5.78,7.05,;-1.61,1.79,;-2.52,.54,;-4.06,.54,;-4.83,-.79,;-1.61,-.7,;-.15,-.23,;1.32,-.7,;2.22,.54,;1.32,1.79,;-.15,1.31,;1.72,-2.19,;3.2,-2.59,;4.29,-1.5,;5.78,-1.9,;3.6,-4.08,;2.51,-5.16,;2.91,-6.65,;4.4,-7.05,;5.49,-5.96,;1.03,-4.77,;.63,-3.28,;-.86,-2.88,;-1.95,-3.97,)| | ||
| Structure | 
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