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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101667 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 45±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM101667 | |||
| n/a | |||
| Name | BDBM101667 | ||
| Synonyms: | US8530504, 29 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H33N3O5S | ||
| Mol. Mass. | 487.612 | ||
| SMILES | COCc1cc(OC)c(-c2csc3c(N(CC4CCC4)C4CCOC4)c(OC)nn23)c(OC)c1 |(5.59,-5.01,;4.5,-6.1,;3.02,-5.7,;2.62,-4.21,;1.13,-3.81,;.73,-2.32,;-.76,-1.92,;-1.84,-3.01,;1.82,-1.23,;1.42,.25,;2.33,1.5,;1.42,2.74,;-.04,2.27,;-1.51,2.74,;-1.91,4.23,;-.82,5.32,;.67,4.92,;1.44,3.59,;2.77,4.36,;2,5.69,;-3.39,4.63,;-4.64,3.73,;-5.88,4.63,;-5.41,6.1,;-3.87,6.1,;-2.41,1.5,;-3.95,1.5,;-4.72,.17,;-1.51,.25,;-.04,.73,;3.31,-1.63,;4.4,-.54,;5.88,-.94,;3.71,-3.12,)| | ||
| Structure | 
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