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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Corticotropin-releasing factor receptor 1 | ||
| Ligand | BDBM101680 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| IC50 | 35±0.0 nM | ||
| Citation |  Shin, K; Terauchi, T; Takahashi, Y; Hashizume, M; Takeda, K; Shikata, K; Inomata, A Pyrazolothiazole compound US Patent US8530504 Publication Date 9/10/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Corticotropin-releasing factor receptor 1 | |||
| Name: | Corticotropin-releasing factor receptor 1 | ||
| Synonyms: | CRF-R | CRF-R2 Alpha | CRF1 | CRFR | CRFR1 | CRFR1_HUMAN | CRH-R 1 | CRHR | CRHR1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing factor receptor 1 (CRF-1) | Corticotropin-releasing factor receptor 1 (CRF1) | Corticotropin-releasing hormone receptor 1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50744.31 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34998 | ||
| Residue: | 444 | ||
| Sequence: |
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| BDBM101680 | |||
| n/a | |||
| Name | BDBM101680 | ||
| Synonyms: | US8530504, 42 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H35N3O5S | ||
| Mol. Mass. | 489.628 | ||
| SMILES | CCOCc1cc(OC)c(-c2csc3c(N(CCCOC)CC4CC4)c(OC)nn23)c(OC)c1 |(1.28,-8.03,;2.37,-6.94,;1.97,-5.46,;3.06,-4.37,;2.66,-2.88,;3.75,-1.79,;3.35,-.3,;4.44,.79,;5.93,.39,;1.86,.1,;1.46,1.58,;2.37,2.83,;1.46,4.08,;,3.6,;-1.46,4.08,;-1.86,5.56,;-.77,6.65,;.71,6.25,;1.8,7.34,;3.29,6.94,;4.38,8.03,;-3.35,5.96,;-4.44,4.87,;-5.93,4.47,;-4.84,3.38,;-2.37,2.83,;-3.91,2.83,;-4.68,1.5,;-1.46,1.58,;,2.06,;.77,-.99,;-.71,-.59,;-1.8,-1.68,;1.17,-2.48,)| | ||
| Structure | 
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