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TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
LigandBDBM101767
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
IC50 4e+1±n/a nM
Citation Fukuoka, MYokogawa, TMiyahara, SMiyakoshi, HYano, WTaguchi, JTakao, Y Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity US Patent US8530490 Publication Date 9/10/2013
More Info.:Get all data from this article,  Assay Method
 
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Name:Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Synonyms:DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase
Type:Enzyme
Mol. Mass.:26574.03
Organism:Homo sapiens (Human)
Description:P33316
Residue:252
Sequence:
MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSA
GRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLS
EHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKH
FIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTE
RGSGGFGSTGKN
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  Blast E-value cutoff:
BDBM101767
n/a
NameBDBM101767
Synonyms:US8530490, 27
TypeSmall organic molecule
Emp. Form.C21H29N3O6S
Mol. Mass.451.536
SMILESCC[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OCC2CC2)c1 |r|
Structure
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