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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Fibroblast growth factor receptor 3 | ||
| Ligand | BDBM102512 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Kinase Assay | ||
| IC50 | 22±0.0 nM | ||
| Citation |  Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Fibroblast growth factor receptor 3 | |||
| Name: | Fibroblast growth factor receptor 3 | ||
| Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
| Type: | Protein | ||
| Mol. Mass.: | 87699.57 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P22607 | ||
| Residue: | 806 | ||
| Sequence: |
| ||
| BDBM102512 | |||
| n/a | |||
| Name | BDBM102512 | ||
| Synonyms: | US8536175, 31 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H28Cl2N6O3 | ||
| Mol. Mass. | 567.466 | ||
| SMILES | COc1cc(OC)c(Cl)c(c1Cl)-c1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cn2)c2nccnc12 |(10.38,-2.67,;8.84,-2.67,;8.07,-1.33,;8.84,,;8.07,1.33,;8.84,2.67,;8.07,4,;6.53,1.33,;5.76,2.67,;5.76,,;6.53,-1.33,;5.76,-2.67,;4.22,,;3.45,1.33,;1.91,1.33,;1.14,,;-.4,,;-1.17,1.33,;-1.17,-1.33,;-2.71,-1.33,;-3.48,,;-5.02,,;-5.79,-1.33,;-7.33,-1.33,;-8.1,,;-7.33,1.33,;-8.08,2.65,;-9.61,2.65,;-10.38,3.98,;-10.36,1.33,;-9.64,,;-5.02,-2.67,;-3.48,-2.67,;1.91,-1.33,;1.14,-2.67,;1.91,-4,;3.45,-4,;4.22,-2.67,;3.45,-1.33,)| | ||
| Structure | 
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