Reaction Details | |||
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Target | Fibroblast growth factor receptor 3 | ||
Ligand | BDBM102542 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Kinase Assay | ||
IC50 | 11±0.0 nM | ||
Citation | Furet, P; Graus Porta, D; Guagnano, V Quinoxaline carboxamide derivatives as protein tyrosine kinase inhibitors US Patent US8536175 Publication Date 9/17/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Fibroblast growth factor receptor 3 | |||
Name: | Fibroblast growth factor receptor 3 | ||
Synonyms: | CD_antigen: CD333 | FGFR-3 | FGFR3 | FGFR3_HUMAN | Fibroblast growth factor receptor | Fibroblast growth factor receptor 3 (FGFR3) | JTK4 | ||
Type: | Protein | ||
Mol. Mass.: | 87699.57 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P22607 | ||
Residue: | 806 | ||
Sequence: |
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BDBM102542 | |||
n/a | |||
Name | BDBM102542 | ||
Synonyms: | US8536175, 153 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H22ClFN6O3 | ||
Mol. Mass. | 484.911 | ||
SMILES | COc1cc(OC)c(Cl)c(c1F)-c1ccc(C(=O)Nc2ncc(CN(C)C)[nH]2)c2nccnc12 |(7.42,4,;8.19,2.67,;7.42,1.33,;8.19,,;7.42,-1.33,;8.19,-2.67,;9.73,-2.67,;5.88,-1.33,;5.11,-2.67,;5.11,,;5.88,1.33,;5.11,2.67,;3.57,,;2.8,1.33,;1.26,1.33,;.49,,;-1.05,,;-1.82,1.33,;-1.82,-1.33,;-3.36,-1.33,;-4.26,-.09,;-5.73,-.56,;-5.73,-2.1,;-7.06,-2.87,;-8.4,-2.1,;-9.73,-2.87,;-8.4,-.56,;-4.26,-2.58,;1.26,-1.33,;.49,-2.67,;1.26,-4,;2.8,-4,;3.57,-2.67,;2.8,-1.33,)| | ||
Structure |