| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidase 1 |
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| Ligand | BDBM103021 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Activity Assay |
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| IC50 | 13.3±0.0 nM |
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| Citation |  Robinson, C; Zhang, J; Garrod, DR; Perrior, TR; Newton, GK; Jenkins, K; Beevers, RE; Major, MR; Stewart, MR Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use US Patent US8541363 Publication Date 9/24/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidase 1 |
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| Name: | Peptidase 1 |
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| Synonyms: | DERP1 | PEPT1_DERPT | Peptidase 1 (Der p 1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36101.04 |
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| Organism: | Dermatophagoides pteronyssinus (European house dust mite) |
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| Description: | P08176 |
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| Residue: | 320 |
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| Sequence: | MKIVLAIASLLALSAVYARPSSIKTFEEYKKAFNKSYATFEDEEAARKNFLESVKYVQSN
GGAINHLSDLSLDEFKNRFLMSAEAFEHLKTQFDLNAETNACSINGNAPAEIDLRQMRTV
TPIRMQGGCGSCWAFSGVAATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEY
IQHNGVVQESYYRYVAREQSCRRPNAQRFGISNYCQIYPPNVNKIREALAQTHSAIAVII
GIKDLDAFRHYDGRTIIQRDNGYQPNYHAVNIVGYSNAQGVDYWIVRNSWDTNWGDNGYG
YFAANIDLMMIEEYPYVVIL
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| BDBM103021 |
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| n/a |
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| Name | BDBM103021 |
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| Synonyms: | US8541363, PVA-038 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H41N5O5 |
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| Mol. Mass. | 515.6449 |
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| SMILES | CC(C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)c1ccncc1)C(C)(C)C)C(=O)C(=O)NC1CCCCC1 |r| |
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| Structure | 
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