Reaction Details | |||
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Report a problem with these data | |||
Target | Cathepsin L2 | ||
Ligand | BDBM103352 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | In Vitro Inhibition Assay | ||
Ki | >10000±0.0 nM | ||
Citation | Quibell, M; Watts, JP; Flinn, NS Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors US Patent US8552202 Publication Date 10/8/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Cathepsin L2 | |||
Name: | Cathepsin L2 | ||
Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V | ||
Type: | Enzyme | ||
Mol. Mass.: | 37341.06 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O60911 | ||
Residue: | 334 | ||
Sequence: |
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BDBM103352 | |||
n/a | |||
Name | BDBM103352 | ||
Synonyms: | US8552202, Compound 4 | ||
Type | Small organic molecules | ||
Emp. Form. | C22H28N2O4 | ||
Mol. Mass. | 384.4687 | ||
SMILES | C[C@H]1CCC(CC1)[C@H](NC(=O)c1ccccc1)C(=O)N1CC[C@H]2OCC(=O)[C@@H]12 |r,wU:7.8,27.29,22.24,wD:1.0,(.08,4.62,;.08,3.08,;-1.25,2.31,;-1.25,.77,;.08,,;1.42,.77,;1.42,2.31,;.08,-1.54,;-1.25,-2.31,;-2.58,-1.54,;-2.58,,;-3.92,-2.31,;-5.25,-1.54,;-6.59,-2.31,;-6.59,-3.85,;-5.25,-4.62,;-3.92,-3.85,;1.42,-2.31,;1.42,-3.85,;2.75,-1.54,;2.75,,;4.22,.48,;5.12,-.77,;6.59,-1.25,;6.59,-2.79,;5.12,-3.26,;4.35,-4.6,;4.22,-2.02,)| | ||
Structure |