| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin L2 |
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| Ligand | BDBM103357 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay |
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| Ki | 2000±0.0 nM |
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| Citation |  Quibell, M; Watts, JP; Flinn, NS Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors US Patent US8552202 Publication Date 10/8/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin L2 |
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| Name: | Cathepsin L2 |
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| Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V |
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| Type: | Enzyme |
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| Mol. Mass.: | 37341.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60911 |
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| Residue: | 334 |
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| Sequence: | MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE
LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW
RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG
GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV
ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK
NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV
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| BDBM103357 |
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| n/a |
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| Name | BDBM103357 |
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| Synonyms: | US8552202, Compound 8 |
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| Type | Small organic molecules |
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| Emp. Form. | C22H25FN6O4 |
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| Mol. Mass. | 456.4701 |
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| SMILES | F[C@H]1CN([C@H]2[C@@H]1OCC2=O)C(=O)[C@@H](NC(=O)c1cccc(c1)-n1cnnn1)C1CCCCC1 |r| |
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| Structure | 
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