Reaction Details | |||
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Report a problem with these data | |||
Target | Cathepsin L2 | ||
Ligand | BDBM103366 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | In Vitro Inhibition Assay | ||
Ki | >10000±0.0 nM | ||
Citation | Quibell, M; Watts, JP; Flinn, NS Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors US Patent US8552202 Publication Date 10/8/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Cathepsin L2 | |||
Name: | Cathepsin L2 | ||
Synonyms: | CATL2 | CATL2_HUMAN | CTSL2 | CTSU | CTSV | Cathepsin U | Cathepsin V | ||
Type: | Enzyme | ||
Mol. Mass.: | 37341.06 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O60911 | ||
Residue: | 334 | ||
Sequence: |
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BDBM103366 | |||
n/a | |||
Name | BDBM103366 | ||
Synonyms: | US8552202, Compound 15 | ||
Type | Small organic molecules | ||
Emp. Form. | C25H29FN4O4 | ||
Mol. Mass. | 468.5206 | ||
SMILES | C[C@H]1CC[C@@H](CC1)[C@H](NC(=O)c1cccc(c1)-n1ccnc1)C(=O)N1C[C@H](F)[C@H]2OCC(=O)[C@@H]12 |r,wU:7.8,33.36,28.31,4.4,wD:26.29,1.0,(1.93,4.62,;1.93,3.08,;.6,2.31,;.6,.77,;1.93,,;3.27,.77,;3.27,2.31,;1.93,-1.54,;.6,-2.31,;-.73,-1.54,;-.73,,;-2.07,-2.31,;-2.07,-3.85,;-3.4,-4.62,;-4.73,-3.85,;-4.73,-2.31,;-3.4,-1.54,;-6.07,-1.54,;-7.53,-2.02,;-8.44,-.77,;-7.53,.48,;-6.07,,;3.27,-2.31,;3.27,-3.85,;4.6,-1.54,;4.6,,;6.07,.48,;6.84,1.81,;6.97,-.77,;8.44,-1.25,;8.44,-2.79,;6.97,-3.26,;6.2,-4.6,;6.07,-2.02,)| | ||
Structure |