Reaction Details |
| Report a problem with these data |
Target | Fucose-binding lectin PA-IIL |
---|
Ligand | BDBM104003 |
---|
Substrate/Competitor | n/a |
---|
IC50 | 4.97e+4± 3.69e+4 nM |
---|
Citation | Hauck, D; Joachim, I; Frommeyer, B; Varrot, A; Philipp, B; Möller, HM; Möller, A; Exner, TE; Titz, A Discovery of two classes of potent glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes. ACS Chem Biol8:1775-84 (2013) [PubMed] Article |
---|
More Info.: | Get all data from this article |
---|
|
Fucose-binding lectin PA-IIL |
---|
Name: | Fucose-binding lectin PA-IIL |
Synonyms: | LecB | PA-IIL |
Type: | Protein |
Mol. Mass.: | 11857.84 |
Organism: | Pseudomonas aeruginosa |
Description: | Q9HYN5 |
Residue: | 115 |
Sequence: | MATQGVFTLPANTRFGVTAFANSSGTQTVNVLVNNETAATFSGQSTNNAVIGTQVLNSGS
SGKVQVQVSVNGRPSDLVSAQVILTNELNFALVGSEDGTDNDYNDAVVVINWPLG
|
|
|
BDBM104003 |
---|
n/a |
---|
Name | BDBM104003 |
Synonyms: | LecB Inhibitor Sulfonamides 5b |
Type | Small organic molecule |
Emp. Form. | C14H21NO7S |
Mol. Mass. | 347.384 |
SMILES | COC1O[C@H](CNS(=O)(=O)c2ccc(C)cc2)[C@@H](O)C(O)[C@@H]1O |r| |
Structure |
|