Reaction Details |
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Target | Dual specificity tyrosine-phosphorylation-regulated kinase 2 [393-601] |
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Ligand | BDBM104065 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Kinome Profiling |
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IC50 | 1800±0.0 nM |
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Citation | Carlson, DA; Franke, AS; Weitzel, DH; Speer, BL; Hughes, PF; Hagerty, L; Fortner, CN; Veal, JM; Barta, TE; Zieba, BJ; Somlyo, AV; Sutherland, C; Deng, JT; Walsh, MP; Macdonald, JA; Haystead, TA Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor. ACS Chem Biol8:2715-23 (2013) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity tyrosine-phosphorylation-regulated kinase 2 [393-601] |
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Name: | Dual specificity tyrosine-phosphorylation-regulated kinase 2 [393-601] |
Synonyms: | DYRK2 | DYRK2_HUMAN | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) |
Type: | Protein |
Mol. Mass.: | 22899.89 |
Organism: | Homo sapiens (Human) |
Description: | Q92630[393-601] |
Residue: | 209 |
Sequence: | VILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRA
KNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFL
KQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVKRITESTGAITSISKLPPPSSS
ASKLRTNLAQMTDANGNIQQRTVLPKLVS
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BDBM104065 |
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n/a |
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Name | BDBM104065 |
Synonyms: | HS38 |
Type | Small organic molecule |
Emp. Form. | C14H12ClN5O2S |
Mol. Mass. | 349.795 |
SMILES | CC(Sc1nc2n(ncc2c(=O)[nH]1)-c1cccc(Cl)c1)C(N)=O |
Structure |
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