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TargetDNA polymerase beta
LigandBDBM104089
Substrate/Competitorn/a
Meas. Tech.DNA Pol β PEX Assay
pH7.9±n/a
IC50 1.82e+4± 0 nM
Commentsextracted
Citation Strittmatter TBrockmann APott MHantusch ABrunner TMarx A Expanding the Scope of Human DNA Polymerase and Inhibitors. ACS Chem Biol 9:282-90 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
DNA polymerase beta
Name:DNA polymerase beta
Synonyms:DNA polymerase beta (Pol β)
Type:Protein
Mol. Mass.:38188.76
Organism:Homo sapiens (Human)
Description:n/a
Residue:335
Sequence:
MSKRKAPQETLNGGITDMLTELANFEKNVSQAIHKYNAYRKAASVIAKYPHKIKSGAEAK
KLPGVGTKIAEKIDEFLATGKLRKLEKIRQDDTSSSINFLTRVSGIGPSAARKFVDEGIK
TLEDLRKNEDKLNHHQRIGLKYFGDFEKRIPREEMLQMQDIVLNEVKKVDSEYIATVCGS
FRRGAESSGDMDVLLTHPSFTSESTKQPKLLHQVVEQLQKVHFITDTLSKGETKFMGVCQ
LPSKNDEKEYPHRRIDIRLIPKDQYYCGVLYFTGSDIFNKNMRAHALEKGFTINEYTIRP
LGVTGVAGEPLPVDSEKDIFDYIQWKYREPKDRSE
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  Blast E-value cutoff:
BDBM104089
n/a
NameBDBM104089
Synonyms:(Z)-5-(3-Nitro-4-(o-tolylthio)benzylidene)-2-thioxothiazolidin-4-one 23 | DNA polymerase inhibitor 23
TypeSmall organic molecule
Emp. Form.C17H12N2O3S3
Mol. Mass.388.484
SMILESCc1ccccc1Sc1ccc(C=C2SC(S)=NC2=O)cc1[N+]([O-])=O |w:12.12,c:17|
Structure
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