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TargetGag-Pol polyprotein [484-582,I494L,I497V,V499I,D514N,E519D,R541K,D544E,Q553K,N572D,L573M]
LigandBDBM104103
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
Ki 0.383±0.097 nM
Citation Shen, YAltman, MDAli, ANalam, MNCao, HRana, TMSchiffer, CATidor, B Testing the substrate-envelope hypothesis with designed pairs of compounds. ACS Chem Biol8:2433-41 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Gag-Pol polyprotein [484-582,I494L,I497V,V499I,D514N,E519D,R541K,D544E,Q553K,N572D,L573M]
Name:Gag-Pol polyprotein [484-582,I494L,I497V,V499I,D514N,E519D,R541K,D544E,Q553K,N572D,L573M]
Synonyms:HIV-1 protease M2 | HIV-1 protease drug-resistant mutant 2 | POL_HV196 | gag-pol
Type:Protein
Mol. Mass.:10757.68
Organism:Human immunodeficiency virus
Description:Q9QBY3[484-582,I494L,I497V,V499I,D514N,E519D,R541K,D544E,Q553K,N572D,L573M]
Residue:99
Sequence:
PQITLWQRPLVTVKIGGQLREALLDTGADNTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QVLIEICGKKAIGTVLVGPTPVNIIGRDMLTQIGCTLNF
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BDBM104103
n/a
NameBDBM104103
Synonyms:N-[(1S,2R)-3-[(6-Benzothiazolylsulfonyl)(cyclohexylmethyl)amino]-2-hydroxy-1- (phenylmethyl)propyl]-3-hydroxy-benzamide (AF-72)
TypeSmall organic molecule
Emp. Form.C31H35N3O5S2
Mol. Mass.593.757
SMILESO[C@H](CN(CC1CCCCC1)S(=O)(=O)c1ccc2ncsc2c1)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1 |r|
Structure
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