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TargetHIV-1 protease M4
LigandBDBM104103
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
Ki 4.823±3.116 nM
Citation Shen YAltman MDAli ANalam MNCao HRana TMSchiffer CATidor B Testing the substrate-envelope hypothesis with designed pairs of compounds. ACS Chem Biol 8:2433-41 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
HIV-1 protease M4
Name:HIV-1 protease M4
Synonyms:HIV-1 protease drug-resistant mutant 4
Type:Protein
Mol. Mass.:10771.71
Organism:Human immunodeficiency virus
Description:n/a
Residue:99
Sequence:
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGVGGFIKVKQYE
QVLIEICGKKVIGTVLVGPTPVNIIGRNMLTQIGCTLNF
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BDBM104103
n/a
NameBDBM104103
Synonyms:N-[(1S,2R)-3-[(6-Benzothiazolylsulfonyl)(cyclohexylmethyl)amino]-2-hydroxy-1- (phenylmethyl)propyl]-3-hydroxy-benzamide (AF-72)
TypeSmall organic molecule
Emp. Form.C31H35N3O5S2
Mol. Mass.593.757
SMILESO[C@H](CN(CC1CCCCC1)S(=O)(=O)c1ccc2ncsc2c1)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1 |r|
Structure
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