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TargetHIV-1 protease M4
LigandBDBM104110
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
Ki 13.53±4.10 nM
Citation Shen YAltman MDAli ANalam MNCao HRana TMSchiffer CATidor B Testing the substrate-envelope hypothesis with designed pairs of compounds. ACS Chem Biol 8:2433-41 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
HIV-1 protease M4
Name:HIV-1 protease M4
Synonyms:HIV-1 protease drug-resistant mutant 4
Type:Protein
Mol. Mass.:10771.71
Organism:Human immunodeficiency virus
Description:n/a
Residue:99
Sequence:
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGVGGFIKVKQYE
QVLIEICGKKVIGTVLVGPTPVNIIGRNMLTQIGCTLNF
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BDBM104110
n/a
NameBDBM104110
Synonyms:3-Hydroxy-N-[(1S,2R)-2-hydroxy-3-[[[5-(5-isoxazolyl)-2-thienyl]sulfonyl](2- methylbutyl)amino]-1-(phenylmethyl)propyl]-benzamide (AF-80)
TypeSmall organic molecule
Emp. Form.C28H31N3O6S2
Mol. Mass.569.692
SMILESCC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(O)c1)S(=O)(=O)c1ccc(s1)-c1ccno1 |r|
Structure
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