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Target5-lipoxygenase/FLAP
LigandBDBM104521
Substrate/Competitorn/a
Meas. Tech.Binding Assay
IC50 2.1±0.0 nM
Citation Bartolozzi ABosanac TChen ZDe Lombaert SDines JAHuber JDLiu WWLoke PLMorwick TMOlague ARiether DTye HWu LZindell RM Oxadiazole inhibitors of leukotriene production US Patent  US8575201 Publication Date 11/5/2013
More Info.:Get all data from this article,  Assay Method
 
5-lipoxygenase/FLAP
Name:5-lipoxygenase/FLAP
Synonyms:5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | FLAP | MK-886-binding protein
Type:Enzyme
Mol. Mass.:18159.90
Organism:Homo sapiens (Human)
Description:P20292
Residue:161
Sequence:
MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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  Blast E-value cutoff:
BDBM104521
n/a
NameBDBM104521
Synonyms:US8575201, 12
TypeSmall organic molecule
Emp. Form.C24H26N8O2
Mol. Mass.458.5156
SMILESCC(C)(O)CNc1ccc(cn1)-c1nc(no1)C1(CCC1)c1ccc(nc1)-c1cnc(N)nc1
Structure
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