| Reaction Details |
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 | Report a problem with these data |
| Target | Kininogen-1 |
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| Ligand | BDBM107209 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Ki | 3.5±n/a nM |
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| Citation |  Aebi, J; Binggeli, A; Hertel, C; Konkar, AA; Kuehne, H; Kuhn, B; Maerki, HP; Wang, H Aryl-benzocycloalkyl amide derivatives US Patent US8592426 Publication Date 11/26/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Kininogen-1 |
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| Name: | Kininogen-1 |
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| Synonyms: | BDK | Bradykinin-1 Receptor | KNG | KNG1 | KNG1_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 71962.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P01042 |
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| Residue: | 644 |
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| Sequence: | MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG
KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD
DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE
KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF
NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
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| BDBM107209 |
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| n/a |
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| Name | BDBM107209 |
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| Synonyms: | US8592426, 59 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H22ClFN8O4 |
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| Mol. Mass. | 552.945 |
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| SMILES | COc1cc(on1)C(=O)NC1(CC1)C(=O)NC1CCc2cc(cnc12)-c1cc(Cl)cc(F)c1-c1nnn(C)n1 |
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| Structure | 
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