| Reaction Details |
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 | Report a problem with these data |
| Target | Kininogen-1 |
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| Ligand | BDBM107159 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Calcium Mobilization Assay |
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| IC50 | 24.4±n/a nM |
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| Citation |  Aebi, J; Binggeli, A; Hertel, C; Konkar, AA; Kuehne, H; Kuhn, B; Maerki, HP; Wang, H Aryl-benzocycloalkyl amide derivatives US Patent US8592426 Publication Date 11/26/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Kininogen-1 |
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| Name: | Kininogen-1 |
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| Synonyms: | BDK | Bradykinin-1 Receptor | KNG | KNG1 | KNG1_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 71962.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P01042 |
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| Residue: | 644 |
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| Sequence: | MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG
KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD
DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE
KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF
NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS
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| BDBM107159 |
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| n/a |
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| Name | BDBM107159 |
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| Synonyms: | US8592426, 8 |
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| Type | n/a |
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| Emp. Form. | C23H19ClF4N6O3 |
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| Mol. Mass. | 538.882 |
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| SMILES | Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1ccc2[C@H](CCc2c1)NC(=O)C1(COC1)NC(=O)C(F)(F)F |r| |
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| Structure | 
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