Ki Summary

Reaction Details

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Target

Acetyl-coenzyme A transporter 1

Ligand

BDBM107363

Substrate/Competitor

n/a

Meas. Tech.

Binding Assay

7.4±0

IC50

1.6±0.0 nM

Citation

Maekawa, T; Igawa, H Fused ring compound and use thereof US Patent US8592431 Publication Date 11/26/2013

More Info.:

Get all data from this article, Solution Info, Assay Method

Acetyl-coenzyme A transporter 1

Name:

Acetyl-coenzyme A transporter 1

Synonyms:

ACATN | ACATN_HUMAN | AT1 | Acetyl-coenzyme A transporter 1 (AT1) | SLC33A1

Type:

Enzyme

Mol. Mass.:

60911.27

Organism:

Homo sapiens (Human)

Description:

O00400

Residue:

549

Sequence:

MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
SSWKCKRNN

BDBM107363

n/a

Name

BDBM107363

Synonyms:

US8592431, 163

Type

Small organic molecule

Emp. Form.

C31H34N6O5

Mol. Mass.

570.6389

SMILES

CCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n([C@@H]2CC[C@@H](CC2)OCCO)c2ncnn12 |r,wU:27.29,30.36,(-6.67,2.44,;-5.33,3.21,;-4,2.44,;-2.67,3.21,;-1.33,2.44,;-1.33,.9,;-2.67,.13,;-2.67,-1.41,;-4,-2.18,;-5.33,-1.41,;-5.33,.13,;-4,.9,;-6.67,-2.18,;-8,-1.41,;-9.34,-2.18,;-9.34,-3.72,;-8,-4.49,;-6.67,-3.72,;-5.33,-4.49,;-5.33,-6.03,;-3.87,-6.5,;-3.1,-7.83,;-2.96,-5.26,;-3.87,-4.01,;,3.21,;1.33,2.44,;,4.75,;1.33,5.52,;2.67,4.75,;4,5.52,;4,7.06,;2.67,7.83,;1.33,7.06,;5.33,7.83,;6.67,7.06,;8,7.83,;9.34,7.06,;-1.33,5.52,;-1.65,7.03,;-3.19,7.19,;-3.81,5.79,;-2.67,4.75,)|

Structure