Ki Summary

Reaction Details

Report a problem with these data

Target

Acetyl-coenzyme A transporter 1

Ligand

BDBM107393

Substrate/Competitor

n/a

Meas. Tech.

Binding Assay

7.4±0

IC50

1.5±0.0 nM

Citation

Maekawa, T; Igawa, H Fused ring compound and use thereof US Patent US8592431 Publication Date 11/26/2013

More Info.:

Get all data from this article, Solution Info, Assay Method

Acetyl-coenzyme A transporter 1

Name:

Acetyl-coenzyme A transporter 1

Synonyms:

ACATN | ACATN_HUMAN | AT1 | Acetyl-coenzyme A transporter 1 (AT1) | SLC33A1

Type:

Enzyme

Mol. Mass.:

60911.27

Organism:

Homo sapiens (Human)

Description:

O00400

Residue:

549

Sequence:

MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
SSWKCKRNN

BDBM107393

n/a

Name

BDBM107393

Synonyms:

US8592431, 228

Type

Small organic molecule

Emp. Form.

C35H40N6O5

Mol. Mass.

624.7293

SMILES

CCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n([C@H]2CC[C@@H](CC2)OCC2(CO)CCC2)c2ncnn12 |r,wU:27.29,wD:30.36,(-7.34,1.36,;-6,2.13,;-4.67,1.36,;-3.33,2.13,;-2,1.36,;-2,-.18,;-3.33,-.95,;-3.33,-2.49,;-4.67,-3.26,;-6,-2.49,;-6,-.95,;-4.67,-.18,;-7.34,-3.26,;-8.67,-2.49,;-10,-3.26,;-10,-4.8,;-8.67,-5.57,;-7.34,-4.8,;-6,-5.57,;-6,-7.11,;-4.54,-7.59,;-3.77,-8.92,;-3.63,-6.34,;-4.54,-5.1,;-.67,2.13,;.67,1.36,;-.67,3.67,;.67,4.44,;.67,5.98,;2,6.75,;3.33,5.98,;3.33,4.44,;2,3.67,;4.67,6.75,;6,5.98,;7.34,6.75,;8.67,5.98,;10,6.75,;8.42,7.83,;7.34,8.92,;6.25,7.83,;-2,4.44,;-2.32,5.94,;-3.85,6.1,;-4.48,4.7,;-3.33,3.67,)|

Structure