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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Acetyl-coenzyme A transporter 1 | ||
| Ligand | BDBM107435 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| pH | 7.4±0 | ||
| IC50 | 1.2±0.0 nM | ||
| Citation |  Maekawa, T; Igawa, H Fused ring compound and use thereof US Patent US8592431 Publication Date 11/26/2013 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Acetyl-coenzyme A transporter 1 | |||
| Name: | Acetyl-coenzyme A transporter 1 | ||
| Synonyms: | ACATN | ACATN_HUMAN | AT1 | Acetyl-coenzyme A transporter 1 (AT1) | SLC33A1 | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 60911.27 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O00400 | ||
| Residue: | 549 | ||
| Sequence: |
| ||
| BDBM107435 | |||
| n/a | |||
| Name | BDBM107435 | ||
| Synonyms: | US8592431, 354 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C34H39FN6O5 | ||
| Mol. Mass. | 630.7091 | ||
| SMILES | CCCc1c(Cc2ccc(cc2)-c2ccccc2-c2nc(=O)o[nH]2)c(=O)n([C@H]2CC[C@@H](CC2)OCC(C)(O)CF)c2nc(C)nn12 |r,wU:27.29,wD:30.36,(-7.16,1.78,;-5.82,2.55,;-4.49,1.78,;-3.16,2.55,;-1.82,1.78,;-1.82,.24,;-3.16,-.53,;-3.16,-2.07,;-4.49,-2.84,;-5.82,-2.07,;-5.82,-.53,;-4.49,.24,;-7.16,-2.84,;-8.49,-2.07,;-9.82,-2.84,;-9.82,-4.38,;-8.49,-5.15,;-7.16,-4.38,;-5.82,-5.15,;-5.82,-6.69,;-4.36,-7.17,;-3.59,-8.5,;-3.45,-5.92,;-4.36,-4.68,;-.49,2.55,;.85,1.78,;-.49,4.09,;.85,4.86,;.85,6.4,;2.18,7.17,;3.51,6.4,;3.51,4.86,;2.18,4.09,;4.85,7.17,;6.18,6.4,;7.51,7.17,;6.74,8.5,;8.85,6.4,;8.28,8.5,;9.82,8.5,;-1.82,4.86,;-2.14,6.36,;-3.67,6.53,;-4.44,7.86,;-4.3,5.12,;-3.16,4.09,)| | ||
| Structure | 
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