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TargetSecreted chorismate mutase
LigandBDBM22793
Substrate/Competitorn/a
Meas. Tech.CM Assay
Temperature310.15±n/a K
IC50 2.330e+4± 2.00e+3 nM
Commentsextracted
Citation Jeankumar, VUAlokam, RSridevi, JPSuryadevara, PMatikonda, SSPeddi, SSahithi, SAlvala, MYogeeswari, PSriram, D Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors. Chem Biol Drug Des83:498-506 (2014) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Secreted chorismate mutase
Name:Secreted chorismate mutase
Synonyms:Chorismate mutase (CM) | Chorismate mutase (MTB CM) | Chorismate mutase-related protein | SCMU_MYCTU
Type:Protein
Mol. Mass.:21942.03
Organism:Mycobacterium tuberculosis H37Rv
Description:n/a
Residue:199
Sequence:
MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFK
WRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNP
ASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSL
YQRALTTATQSYCQALPPA
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BDBM22793
n/a
NameBDBM22793
Synonyms:1‐phenylindole‐2,3‐dione (Compound 6) | 1-phenyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-based compound, 13
TypeSmall organic molecule
Emp. Form.C14H9NO2
Mol. Mass.223.2268
SMILESO=C1N(c2ccccc2C1=O)c1ccccc1
Structure
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