| Reaction Details |
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 | Report a problem with these data |
| Target | Secreted chorismate mutase |
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| Ligand | BDBM108074 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | CM Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | >1.00e+5±n/a nM |
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| Comments | extracted |
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| Citation |  Jeankumar, VU; Alokam, R; Sridevi, JP; Suryadevara, P; Matikonda, SS; Peddi, S; Sahithi, S; Alvala, M; Yogeeswari, P; Sriram, D Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors. Chem Biol Drug Des83:498-506 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Secreted chorismate mutase |
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| Name: | Secreted chorismate mutase |
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| Synonyms: | Chorismate mutase (CM) | Chorismate mutase (MTB CM) | Chorismate mutase-related protein | SCMU_MYCTU |
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| Type: | Protein |
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| Mol. Mass.: | 21942.03 |
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| Organism: | Mycobacterium tuberculosis H37Rv |
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| Description: | n/a |
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| Residue: | 199 |
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| Sequence: | MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFK
WRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNP
ASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSL
YQRALTTATQSYCQALPPA
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|
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| BDBM108074 |
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| n/a |
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| Name | BDBM108074 |
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| Synonyms: | (3Z)‐3‐[(6‐nitro‐1,3‐benzothiazol‐2‐yl)imino]‐1H‐ indol‐2‐one (Compound 14) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H8N4O3S |
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| Mol. Mass. | 324.314 |
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| SMILES | [O-][N+](=O)c1ccc2nc(\N=C3/C(=O)Nc4ccccc34)sc2c1 |
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| Structure | 
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