Reaction Details | |||
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Report a problem with these data | |||
Target | Plasminogen | ||
Ligand | BDBM108112 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Inhibition Assay | ||
Ki | 5±0.0 nM | ||
Citation | Herold, P; Daghish, M; Jelakovic, S; Ludwig, F; Reichelt, C; Schulze, A; Schweinitz, A Trypsin-like serine protease inhibitors, and their preparation and use US Patent US8598206 Publication Date 12/3/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Plasminogen | |||
Name: | Plasminogen | ||
Synonyms: | Activation peptide | Angiostatin | PLG | PLMN_HUMAN | Plasmin | Plasmin heavy chain A | Plasmin heavy chain A, short form | Plasmin light chain B | ||
Type: | Enzyme | ||
Mol. Mass.: | 90579.18 | ||
Organism: | Homo sapiens (Human) | ||
Description: | n/a | ||
Residue: | 810 | ||
Sequence: |
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BDBM108112 | |||
n/a | |||
Name | BDBM108112 | ||
Synonyms: | US8598206, Table 6, 21 | ||
Type | Small organic molecule | ||
Emp. Form. | C33H44N7O5S | ||
Mol. Mass. | 650.811 | ||
SMILES | NC(=N)c1ccc(CNC(=O)[C@H](CCC2CCNCC2)NC(=O)[C@@H](CCC2=CC=[N](O)C=C2)NS(=O)(=O)Cc2ccccc2)cc1 |r,wU:23.34,11.20,c:32,t:27,29,(11.34,2.69,;10,3.47,;10,5,;8.67,2.69,;8.67,1.15,;7.34,.38,;6,1.15,;4.67,.38,;3.33,1.15,;2,.38,;2,-1.15,;.67,1.15,;.67,2.69,;2,3.47,;2,5,;3.33,5.78,;3.33,7.31,;2,8.08,;.67,7.31,;.67,5.78,;-.67,.38,;-2,1.15,;-2,2.69,;-3.33,.38,;-3.33,-1.15,;-2,-1.93,;-2,-3.47,;-3.33,-4.23,;-3.33,-5.78,;-2,-6.54,;-2,-8.08,;-.67,-5.78,;-.67,-4.23,;-4.67,1.15,;-6,.38,;-6.77,-.95,;-5.23,-.95,;-7.34,1.15,;-8.67,.38,;-10,1.15,;-11.34,.38,;-11.34,-1.15,;-10,-1.93,;-8.67,-1.15,;6,2.69,;7.34,3.47,)| | ||
Structure |