| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin B |
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| Ligand | BDBM110194 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cathepsin B Inhibition Assay |
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| pH | 5.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 8.459e+4± 375 nM |
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| Comments | extracted |
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| Citation |  Baek, KH; Karki, R; Lee, ES; Na, Y; Kwon, Y Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors. Bioorg Chem51:24-30 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin B |
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| Name: | Cathepsin B |
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| Synonyms: | APP secretase | APPS | CATB_HUMAN | CPSB | CTSB | Cathepsin B heavy chain | Cathepsin B light chain | Cathepsin B1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 37819.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_63102437 |
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| Residue: | 339 |
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| Sequence: | MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCG
TFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDR
ICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCR
PYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIM
AEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSW
NTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
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| BDBM110194 |
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| n/a |
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| Name | BDBM110194 |
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| Synonyms: | 1-(3,5-Dihydroxyphenyl)-3-(furan-2-yl)propenone (21) |
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| Type | Small organic molecule |
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| Emp. Form. | C13H10O4 |
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| Mol. Mass. | 230.2161 |
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| SMILES | Oc1cc(O)cc(c1)C(=O)\C=C\c1ccco1 |
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| Structure | 
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