| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 1 |
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| Ligand | BDBM113726 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Binding Assay |
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| Temperature | 298.15±n/a K |
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| Ki | 0.5±n/a nM |
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| Comments | extracted |
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| Citation |  Santella, JB Piperidinyl derivative as a modulator of chemokine receptor activity US Patent US8633226 Publication Date 1/21/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| C-C chemokine receptor type 1 |
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| Name: | C-C chemokine receptor type 1 |
|---|
| Synonyms: | C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 41180.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32246 |
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| Residue: | 355 |
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| Sequence: | METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLV
QYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSE
IFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTH
HTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRL
IFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVI
YAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
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|
|
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| BDBM113726 |
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| n/a |
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| Name | BDBM113726 |
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| Synonyms: | US8633226, 850 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H34ClN3O3 |
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| Mol. Mass. | 423.977 |
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| SMILES | CC(C)NC(=O)N[C@H](C(C)C)C(=O)N1CC[C@](O)(c2ccc(Cl)cc2)C(C)(C)C1 |r| |
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| Structure | 
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